ea0032p688 | Neuroendocrinology | ECE2013
Jakobsen Line Pickering
, Jennum Poul
, Gammeltoft Steen
, Feldt-Rasmussen Ulla
, Klose Marianne
Hypothesis: We hypothesised that damage to the hypothalamus by local tumour, surgical treatment, or irradiation might involve the suprachiasmatic nucleus and thereby melatonin secretion, leading to disturbed circadian function and clinical manifestations such as daytime sleepiness and fatigue in craniopharyngeoma patients.Objective: We aimed to assess the influence of craniopharyngiomas and their treatment on melatonin secretion, sleep pattern, sleep qua...